Nearly 300 miles of Interstate 25 in Wyoming is closed in both directions due to winter weather.

Most of the stretch between Cheyenne and Buffalo has no estimated reopening time, but WYDOT says the segment between Casper and Buffalo could reopen between 8:30 p.m. and 10:30 p.m. Saturday.

Nearly all of Interstate 80 is closed in the southern portion of the state. I-80 is closed in both directions between Evanston and Rawlins, and from Laramie to Cheyenne. Between Rawlins and Laramie, the westbound lanes are closed with no estimated reopening time, but the eastbound lanes are open, though winter weather is impacting road conditions.

Other closed highways include US 287 between Rawlins and WY 28 south of Lander, WY 220 between Pathfinder Road and Muddy Gap, US 289 between I-80 and WY 372, US 191 between the Utah border and I-80, WY 430 between the Colorado border and Rock Springs, US 18/20 between Lusk and I-25 at Orin Junction, US 85 between Torrington and Cheyenne, WY 210 between Laramie and Cheyenne, US 287 between the Colorado border and Laramie, US 30/287 between Bosler and I-80, WY 387 between Midwest and Wrignt, WY 192 between Kaycee and WY 387, and WY 196 between Buffalo and Kaycee.

For the latest road conditions, visit WyoRoad.info, call 511 or download the Wyoming 511 app.

This developing story will be updated. 

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