UPDATE - Interstate 25 in Cheyenne has reopened following a crash in the southbound lane near Central Avenue.

5:05 P.M. UPDATE - The left lane of southbound Interstate 25 has been reopened, but the right lane is still blocked.

Calls to the Wyoming Highway Patrol seeking comment were not immediately returned.

ORIGINAL STORY:

A portion of Interstate 25 in Cheyenne is closed following a crash in the southbound lane near Central Avenue.

According to the Wyoming Department of Transportation's website, all lanes are blocked.

Drivers should be prepared to stop and expect delays.